The Tepe Lab moved to the University of Virginia in January 2024, from Michigan State University. Our group is made up of highly skilled and diverse people from all over the world. We specialize in synthetic organic chemistry, medicinal chemistry, and chemical biology. The group’s focus is on studying protein degradation systems and developing small molecules to alter them. We also create novel ways to synthesize natural products and their derivatives as possible therapeutic leads. Our overall goal is to develop new therapies for cancer and neurodegenerative diseases.